Stomach cancer, also known as gastric cancer, is a significant health concern worldwide and in Singapore. Statistics show that men are more likely to develop stomach cancer than women. Survival rates are also often better for women than for men. What are the reasons behind this gender disparity and how can men protect themselves against the risk of stomach cancer?
Learn More: Guide To Stomach Cancer In Singapore >>
Why Men Are At Greater Risk of Stomach Cancer
Hormonal Differences
One of the primary reasons men are at greater risk of stomach cancer is hormonal differences. Estrogen, the primary female sex hormone, offers some protection against stomach cancer. It reduces inflammation in the stomach lining and discourages the growth of cancer cells. Women in premenopausal stages tend to have lower risks of developing stomach cancer. However, this risk increases after menopause as estrogen levels decline.
Lifestyle Factors
Lifestyle choices may also play a significant role in the increased risk of stomach cancer in men. It has been theorised that men are more likely to engage in behaviors such as smoking and excessive alcohol consumption, which are known risk factors for stomach cancer. Additionally, men often consume more processed and red meats, which have been linked to an increased risk of stomach cancer.
Genetic Predisposition
Genetic factors may also contribute to the higher incidence of stomach cancer in men. Studies have shown that certain genetic mutations associated with stomach cancer are more prevalent in men. Men with a family history of the disease appear to be at a higher risk, suggesting potential gender-specific genetic patterns.
Epigenetic Changes
Epigenetic changes, which involve modifications to gene expression without altering the DNA sequence, can also influence the risk of stomach cancer. Research has shown that men may have different epigenetic profiles compared to women, making them more susceptible to stomach cancer.
Importance Of Stomach Cancer Screening
Early detection of stomach cancer is crucial for improving treatment outcomes. Regular screenings, such as gastroscopy, can help identify cancer at an early stage, before symptoms become severe. Gastroscopy is considered the gold standard for stomach cancer screening, as it allows doctors to directly visualise the stomach lining and detect any abnormalities. Polyps detected during a gastroscopy can be removed during the procedure for further investigation and to prevent them from becoming cancerous.
For those who are hesitant to undergo gastroscopy, there is an alternative: the GastroClear blood test. This non-invasive test can help detect stomach cancer by identifying specific biomarkers in the blood. While it may not be as comprehensive as gastroscopy, it provides a valuable option for those seeking a less invasive screening method.
Learn More: Stomach Cancer Screening In Singapore >>
Contact Us For A Doctor’s Appointment
Understanding the factors that contribute to the higher risk of stomach cancer in men is essential for developing targeted prevention and screening strategies. Hormonal differences, lifestyle choices, genetic predisposition, and epigenetic changes all play a role in this gender disparity. Men aged 40+ can protect themselves against their higher risk of stomach cancer by going for regular screenings. Early detection can improve treatment outcomes. Contact us via the button below for an appointment with a doctor for gastroscopy stomach cancer screening.
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This article is informative only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment, and should never be relied upon for specific medical advice.